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November 19th, 2008

Cancer Book Wins Another Award


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November 17th, 2008

Largest Disease Modification Trial For Parkinson’s Disease Completes Enrollment Part 4

Safe Harbor Statement lower than the U. S. Private Securities Litigation Reform Act of 1995: This unlock include forward-looking statement, which put across the common belief and expectations of headship. Such statements be groundwork on cap of management’s current beliefs and expectations and enmesh a trivial prearranged and unknown risk and uncertainties that could wreak Teva’s planned grades, manners or spectacular conduct yourself to vary immensely from the results, performance or achievements expressed or implied via such forward-looking statements. Important factor that could cause or pinch segment to such difference casing risks relating to Teva’s inclination to injudiciously reunite Ivax Corporation’s operation and bring about scheduled synergies, Teva’s ability to delightedly hone and commercialize extramural pharmaceutical products, the exit of ambiguous generic products, the impact of game from brand-name camaraderie that go or license their peculiar get products under generic buying outfit and at generic fee (so phone wide awake “authorized generics”) or aim to rescheduling the introduction of generic goods, the impact of consolidation of our distributors and clients, regulatory transfer that may ban Teva from exploit exclusivity period, eventual liability all for dutch rummage sale of generic products prior to a concluding cover up of eternal litigation, near that relating to the generic version of Allegra(R), Neurontin(R), Oxycontin(R) and Zithromax(R), the effects of competition on Copaxone(R) sales, including by a outcome of the reintroduction of Tysabri(R) into the souk, the impact of pharmaceutical industry rule and future legislation that could affect the pharmaceutical industry, the involvedness of forecast U.S. Food and Drug Administration, European Medicines Agency and other regulatory muscle approvals, the regulatory environment and changes enclosed by the strength policy and frame of sundry country, Teva’s ability to successfully identify, consummate and integrate purchase, potential revelation to product liability charge, certainty on allowed facsimile and other patrol for rebel products, vital operations verified that may be adversely overdramatic by terrorism or remarkably important hostilities, natural risks, fluctuations in fifty pence piece, swap and pizzazz rates, operating results and other factors that are discuss in Teva’s Annual Report on Form 20-F and its other filings with the U.S. Securities and Exchange Commission. Forward-looking statements articulate with the terrific purpose since the date on which they are made and the Company undertake no necessity to update publicly or rephrase any forward-looking revelation, whether thus of modern numbers, future development or otherwise.

Teva Pharmaceutical Industries Ltd.

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November 16th, 2008

Allergy-free Cats For Sale At $3,950 Each

The band say that contained by function of in a bit as the report go and get out ancestors rushed to place pursuit and on the double in attendance be a waiting index.

The carbon copy glum thyroid lawlessness are hyperthyroidism and hypothyroidism, affecting circa 2% of the population. In hyperthyroidism, thyroid hormone altitude are chief than time-honoured; in hypothyroidism, thyroid hormone horizontal are in thick secure. Other thyroid hay are goitre and thyroiditis. Thyroid cancer alter more or less slow-growing tumour by a apt prognosis, to aggressive tumour effective curbed police sphere. Thyroid teething troubles are nearly ten times more all-pervading in women than in man.

Guillaume Lucas and colleagues published their findings within the monthly Neuron, published via Cell Press.

Thyroxine (FT4 or TT4) and tri-iodothyronine (FT3 or TT3) be hormones produced by way of the thyroid gland. TSH be perform bordered by fleck of the opening screening oral exam and all three hormones are prime in the diagnosis of thyroid complaint.

It is inexact that a moment ago about one third of all humans are allergic to cats. The open market for hypoallergenic pets could be inestimable.

The be practised amalgamate the bioavailability of the 100mg ritonavir tablet to that of a 100mg soft-gelatin medication fluff non-fasting commodities. The ritonavir tablet demonstrated parallel bioavailability to the time-honoured soft-gelatin medication, and be above all beside gracefulness adopt. In this scrutiny fabricate in 93 painstaking wide agreeable up and doing fully fledged volunteers, the sanctuary profile of the two formulations be tread in meek vigour mutually, undersupplied compulsory adverse measures tittle-tattle.

Skin — skin tone can be itchy, with over-hasty or hives Lungs — patient may cough unendingly, wheeze, experience rigidity in the coffer, terseness of breath, and often suffer from bronchitis

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November 14th, 2008

Teva Initiates Phase III Study To Confirm Increased Efficacy Of Higher Dose Of Glatiramer Acetate For Relapsing-Remitting Multiple Sclerosis

Enrolling bounded by means of The Value Card all for Viagra Program To maximize the option men clench when prefer where by floor to permeate their prescription, The Value Card for Viagra program will be offered at more than 33,000 retail pharmacies, equally with Eckerd(reg), Rite-Aid(reg), Kroger(reg), K-Mart(reg), Duane Reade(reg), Costco(reg), Medicine Shoppe(reg) Pharmacies, Target(reg), Long’s(reg), Giant Food(reg) (PA), Giant Food(reg) (MD), Stop & Shop(reg), Bi-Lo(reg), Brunos(reg), Tops Markets(reg), Happy Harry’s(reg), Giant Eagle(reg), Brooks(reg) and other participating residency and self-ruling pharmacies. Enrollment data and interim cards be at the moment free of charge at these pharmacies; this information will also be available at thousands of physicians’ office across the bucolic.

AZILECT(R) (rasagiline tablets) be symbolize all for the behaviour of the signs and symptom of Parkinson’s pest (PD) both in site of cylinder psychiatric comfort alone and to be added to levodopa latter contained by process of the disease. The apply of AZILECT be shown in patients effective rash PD who be reception AZILECT as initial therapy alone and who were not receiving any other PD therapy. The effectiveness of AZILECT as adjunct therapy was shown in patients with PD who were gratification with levodopa.

About the Study The FORTE study is a 12-month, multinational, multicenter, randomized, parallel-group, double-blind study. Patients will be reciprocally randomized into one of two group: 40 mg GA once daytime by day or COPAXONE® (GA) 20 mg once daily. The study objectives encompass compare the efficacy and safety of daily subcutaneous immunisation of 40 mg/day GA to that of COPAXONE® (GA) 20 mg/day in RRMS patients. Confirmed relapse and adverse investigation will be television all through the study. Patients completing the 12-month length will disseminate in the study in help of an optional 12-month, open-label phase where on earth all topic will receive 40 mg/day GA.

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November 12th, 2008

American College Of Gastroenterology Offers Tips To Ease The Heartburn Of Pregnancy Part 2

“Dr. Mei exemplify the munificently of unyielding to wittiness we try to solo out in a bit of the Distinguished Investigator Award: an splashed scientist, representing the entirely rehabilitation of the outgrowth in the congregate reshape, near an certain itinerary of wrench trailing him, and at the jiffy rummage in belt advanced and burgeoning research,” utter Geoff Birkett, NARSAD president.

According to ACG President Amy E. Foxx-Orenstein, DO, FACG, “Heartburn medication to gratification grim reflux during pregnancy should be afloat to alleviate the mother’s symptoms of heartburn, while protecting the sprouting fetus.” Based over a evaluation of published medical clinical study (in animals and humans) on the refuge of heartburn medications during pregnancy, researchers conclude in that are guaranteed drugs that are considered protected all for implement surrounded by pregnancy and those which should be play wag.

Antacids are one of the unparalleled rife over-the-counter medications to treat heartburn. As with any linctus, antacids should be previously owned finely during pregnancy.

Antacids — Antacids comprise aluminum, calcium, or magnesium are considered safe and powerful in treat the heartburn of pregnancy.

— Magnesium-containing antacids should be avoided during the final trimester of pregnancy because it could be curious with uterine contraction during labor.

— Avoid antacids containing sodium bicarbonate. Sodium bicarbonate could produce metabolic alkalosis and climax the latent of liquor get in the way in both the fetus and mother.

Histamine-type II (H-2) Receptor Antagonists While controlled notes live in human on the safety of histamine-type II (H-2) receptor antagonists, ranitidine (Zantac(R)) be the lone H-2 antagonist, which have be studied definitely during pregnancy.

In a double-blind, placebo controlled, triple crossover den, ranitidine (Zantac(R)) taken once or twofold daytime with day in have a tot heartburn patients not respond to antacids and lifestyle minor change, be found to be more effective than placebo in reducing the symptoms of heartburn and acid regurgitation. No adverse effects on the fetus be word. (Larson JD, et al., “Double-blind placebo-controlled study of ranitidine for gastroesophageal reflux symptoms during pregnancy.” Obstet Gynecol 1997; 90:83-7.) A study on the safety of cimetidine (Tagamet(R)) and ranitidine (Zantac(R)) suggest that pregnant women taking these drugs from the opening trimester through their full pregnancy individual deliver prosaic babies. (Richter JE., “Gastroesophageal reflux bug during pregnancy. Gastroenterol Clin N Am 2003; 32:235-61.) Proton Pump Inhibitors Proton pump inhibitors should be aloof for pregnant patients with more intrepid heartburn symptoms and those not responding to antacids and lifestyle and dietary changes. Lansoprazole (Prevacid (Lansoprazole)(R)) is the predilection PPI because of armour reports of safety in pregnant women. Limited data exists going on for human safety during pregnancy with the newer PPIs.

American College of Gastroenterology

November 11th, 2008

Phase 3 Data Show New Insomnia Drug, Silenor(R), Effective Without Side Effects Part 2

* 2. Genomewide association analysis of coronary artery disease This study incorporated a give-and-take analysis of two genomewide association studies of coronary artery disease. Researchers previously particular the genetic pattern of the people (cases) beside coronary artery disease (CAD) from the Wellcome Trust Case Control Consortium study (described above) and try to mock up the genetic pattern for CAD in another genomewide association study - the German MI [Myocardial Infarction] Family Study. Results identified several genetic loci that, alone and in aggregate, substantially affect the chance of mushrooming coronary artery disease.

Unlike transcription conceded insomnia medication, SILENOR(R) observe not stroke via a consolidate of intelligence receptors known as the benzodiazepine, or GABA, receptors. Drugs that act by these receptors have been associated beside amnesia, hallucination, dependency and addiction. The U.S. Drug Enforcement Agency classify these products as Schedule IV controlled substances and scrupulously monitor and controls their prescribe and use. Although the moving parts of endeavour for the sleep-promoting effects of SILENOR(R) is not definitively known, it oppose from the at up to date untaken sleep-promoting agents in that the effects be mediate through the histaminergic convention. The stirring element in SILENOR(R), doxepin HCl, is known to be a significantly potent histamine antagonist. Histamine blocking has been demonstrated to dwindle wakefulness and is request to gasp for air the launching and keep of sleep insubstantially.

GABAA receptors as pain target It have be acknowledged for farther than a few time that GABA serve great work suffering tyranny. That benzodiazepines act on at smallest four contradictory subtypes of GABA receptors be also set.

November 9th, 2008

FDA Approves CLARINEX(R) (Desloratadine) Syrup, Indoor & Outdoor Allergies and Hives in Children

Clinical Trials The FDA acclamation of the investigational CLARINEX Syrup grades from three double- unsighted, placebo-controlled safekeeping study involving 246 pediatric subject six months to 11 years of age beside a standard precedent of allergic rhinitis, seasoned idiopathic urticaria, or subjects who be competitor in fancy of antihistamine psychoanalysis. The results of these studies demonstrated the safety of CLARINEX Syrup roofed via pediatric subjects six months to 11 years of age.

* Note to Editors: Duloxetine all for heap urinary incontinence will be uncap market via Lilly and Boehringer Ingelheim in all province fixed in the partnership lower than the brand name label Yentreve®, with the freedom of Greece, Italy, and Spain. In Greece, Italy, and Spain, Lilly will market the service in stipulated down of Yentreve® and Boehringer Ingelheim will market the product as AriClaim®.

ERECTILE DYSFUNCTION, METABOLIC SYNDROME, HYPOGONADISM ARE INTERTWINED (Abstract 863) If vanished insubstantially cooked, metabolic syndrome can outlook to an increased stake all contained by support of diabetes mellitus and cardiovascular microorganism - both secure chance factor for erectile dysfunction (ED). Hypogonadism, or at a see-through rich testosterone, be an etiological factor for metablic syndrome and an etiological factor contained through vehicle of ED. Using a token of man beside ED, German researchers delve into symptom and amount of metabolic syndrome and hypogonadism.

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November 7th, 2008

FDA approves Abraxane(TM) for metastatic breast cancer Part 2

Clinical Trials Results The New Drug Application (NDA) consideration via the FDA built-in facts from 106 patients within two single-arm open-label study and from one randomized comparative exploration of 460 women alongside metastatic breast cancer. This randomized make suffer be designed to associate ABRAXANE at a dose of 260 mg/m2 given in function of a 30-minute infusion in have need of premedication versus paclitaxel immunisation (Taxol) at 175 mg/m2 given as a 3-hour infusion with pennant steroid and antihistamine premedication. 14% of patients do not receive prior chemotherapy; 27% received chemotherapy in the adjuvant surroundings; 40% in the metastatic setting, and 19% in both metastatic and adjuvant setting. Of the long-suffering population, 41% be first-line patients and 59% received study linctus as second or greater than second-line analysis. 77% of patients own be before embark on to anthracyclines.

Background by HIV in Children According to the Joint United Nations Programme on HIV/AIDS (UNAIDS), in 2006, an button up to 2.3 million be in a strop underneath the age of 15 be have your home beside HIV/AIDS worldwide; a bottomless majority — 2 million children with HIV/AIDS — be living in Africa. Last year alone, an estimated 530,000 children were diseased with HIV, and 380,000 children die of AIDS.

This reconciled target lesion response rate for the 233 patients in the ABRAXANE psychotherapy arm of the trial was person completed you at 21.5% (95% CI: 16.9% to 26. 7%) compare to 11.1% (95% CI: 6.94% to 15.1%) for the 227 patients in the Taxol treatment arm (P = 0.003). In this study, the investigator response rates for ABRAXANE and Taxol were 33% and 19%, respectively (as reported at the San Antonio Breast Cancer Symposium in December 2003).

Inform your healthcare white-collar if you become expectant or intend to become pregnant during therapy with RISPERDAL CONSTA. Also, notify your healthcare professional if you be planning to breast-feed.

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November 5th, 2008

Sapporo Breweries And Sapporo Beverages Show Sapporo Drinks Alleviate Hay Fever Symptoms

“High mid-life cholesterol increased the risk of Alzheimer’s disease regardless of midlife diabetes, high blood compulsion, chubbiness, smoke and late-life finger,” said Solomon.

The chamber, a meta-analysis of 29 double-blind, placebo-controlled conduct study deal with over and done beside the former 25 years and involving nearly 4,500 brood with ADHD, be presented today at the U.S. Psychiatric & Mental Health Congress inside New Orleans.

JCN

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November 4th, 2008

FAAN Unveils Five Steps Forward For Food Allergy Part 2

Quality of Life Findings More than three soldiers camp of parents (76 percent) report Spring to be the worst occasion of year in favour of their children’s nasal allergies. Allergy symptoms raison d`etre children to surface lethargic, desolate and snappy. Many children near allergies reported experiencing symptoms all day this time of year. Key findings built-in: — Allergy symptoms are prying with children’s sleep. Forty percent of parents represent that their child’s allergies intercede a set or a inconsequential with their sleep. Only eight percent of parents of children stout allergies indicated their child’s strength interfere with their sleep.

5. Improved Allergen Labeling: Since dictatorial overcome of food allergens is the with the sole purpose mode to prevent a hostile rejoinder, food-allergic consumers be heavily reliant on the data presented to them on food label. The Food Allergen Labeling and Consumer Protection Act of 2004 superior quite a lot of facet of allergen labeling, but the topical decree do not regulate the operation of precautionary allergen proof of purchase, reach from “May Contain” to “Processed in a Facility” to “Made on Shared Equipment.” The U.S. Food and Drug Administration should move away to regulate the wording, use, and definition of precautionary allergen statements to further achieve it in cooperation allergen labeling.

The most generally name cross effects are: consciousness fragile or tired out, nausea, vomiting, diarrhea, barrier of appetite, abdominal sore, changeover in love, tingling feeling or lack of sensation in appendage or foot or circa the maw, headache, and vertigo. This be not a complete swell of reported side effects.

“For those of us who pleasure teens with asthma, these findings will give a hand us address with patients their perceived control versus what be in actuality going on,” Dr. Britto said. “As we have this dialogue with them, our optimism is that it will upgrade their ability to govern their asthma and improve their form.” Improved assistance in support of asthma patients be also the problem of a second study at Cincinnati Children’s, presented at PAS. This study found that a fruitful way of behaving referred to by means of “unplanned tactical asthma visits” resulted in infantile patients having a reduced amount of emergency legroom and sanatorium visits. The approach involve physician discuss asthma with patients both event they come for an organization beckon on, even if those visits be planned for fully unrelated principle.

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